A method for producing taxol and taxanes from embryo...

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 17/02 (2006.01) C12N 5/04 (2006.01)

Patent

CA 2143455

Disclosed herein is methods of taxol and taxane production through extraction of tissue of Taxus species and cell culture thereof. The method of production of taxol and its derivatives by extracting tissues and/or culture medium of Taxus species is characterized in that said tissue is zygote embryo. Cell culture of zygote embryo of Taxus species can be carried out by inducing somatic embryo or embryogenic callus.

L'invention concerne des procédés de production du taxol et de taxanes par extraction de tissus d'espèces appartenant au genre Taxus et de leur milieu de culture. Le procédé de production du taxol et de ses dérivés par extraction des tissus et/ou du milieu de culture d'espèces appartenant au genre Taxus est caractérisé par le fait que ledit tissu est un embryon zygotique. On peut réaliser des cultures cellulaires d'embryons zygotiques d'espèces appartenant au genre Taxus en induisant des embryons somatiques ou des cals embryonnaires.

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