C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2603815
Aspects of the present invention relate to compositions and methods for providing DNA fragments from a remote sample. In particular aspects a remote sample comprising DNA is provided, DNA is isolated from the remote sample, and the isolated DNA is treated in a way which allows differentiation of methylated and unmethylated cytosine. Additional, particular embodiments provide compositions and methods for methylation analysis of DNA derived from a remote sample. Other aspects provide for compositions and methods of whole genome amplification of bisulfite treated DNA.
Certains aspects de cette invention concernent des compositions et des procédés destinés à fournir des fragments d'ADN à partir d'un échantillon à distance. Dans des aspects particuliers de cette invention, un échantillon à distance contient de l'ADN, l'ADN est isolé de l'échantillon à distance, puis traité de manière à permettre la différenciation de cytosine méthylée et non méthylée. En outre, des modes de réalisation particuliers concernent des compositions et des procédés d'analyse de méthylation d'ADN dérivé d'un échantillon à distance. D'autres aspects concernent des compositions et des procédés d'amplification de génome entier d'ADN traité au bisulfite.
Ballhause Matthias
Berlin Kurt
de Vos Theo
Dietrich Dimo
Liebenberg Volker
Epigenomics Ag
Smart & Biggar
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