A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/192 (2006.01) A61K 31/165 (2006.01) A61K 31/4409 (2006.01) A61P 35/00 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2335397
This invention provides a method to identify compounds potentially useful for the treatment and prevention of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with its ability to elevate JNK kinase activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibition, an ability to elevate JNK kinase activity, growth inhibition and apoptosis induction are desirable for the treatment of neoplasia.
Li Han
Liu Li
Soh Jae Won
Thompson W. Joseph
Weinstein I. Bernard
Cassan Maclean
Cell Pathways Inc.
Osi Pharmaceuticals Inc.
LandOfFree
A method for screening compounds for their potential to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method for screening compounds for their potential to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for screening compounds for their potential to... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1354417