C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/50 (2006.01) A61K 38/48 (2006.01) C12N 9/64 (2006.01) C12N 9/96 (2006.01)
Patent
CA 2175202
The present invention is directed to a method for stabilizing protein C or activated protein C and a preparation obtained by said method. Said method and preparation being applicable during procedures such as isolation and purification, lyophilization, heating, etc. or when stored. The method comprises adding to a salt buffer containing protein C or activated protein C and sodium ion at least one amino acid, and further adding either one or a combination of albumin and a non-ionic surfactant.
La présente invention concerne un procédé visant à la stabilisation de la protéine C activée ou non activée pour les opérations de séparation/purification par conductivité, de lyophilisation, de traitement thermique ou de stockage. La composition stabilisée est obtenue par mélange d'un tampon salin contenant la protéine C activée ou non et des ions sodium avec au moins un acide aminé et de l'albumine et/ou un surfactant non ionique.
Akimoto Yoshinori
Miyata Kazumasa
Nakagaki Tomohiro
Ogata Yoichi
Juridical Foundation The Chemo-Sero-Therapeutic Research Institu
Kirby Eades Gale Baker
Teijin Limited
LandOfFree
A method for stabilizing protein c or activated protein c... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method for stabilizing protein c or activated protein c..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for stabilizing protein c or activated protein c... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2048376