A method for the preparation of crystalline dexloxiglumide

C - Chemistry – Metallurgy – 07 – C

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C07C 231/24 (2006.01) C07C 233/12 (2006.01)

Patent

CA 2529018

The present invention describes a novel method for the purification of dexloxiglumide by crystallization from isopropyl ether which permits the production, in a reproducible manner, of a product with morphological and particle-size characteristics such as favour its use in the preparation of oral pharmaceutical forms on an industrial scale.

L'invention décrit un procédé nouveau de purification de dexloxiglumide par cristallisation d'éther d'isopropyle, ce qui permet de produire de manière reproductible un produit avec des caractéristiques morphologiques et granulométriques qui permettent son utilisation pour préparer des formes pharmaceutiques d'administration orale à l'échelle industrielle.

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