C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) C07B 63/00 (2006.01) C07D 211/40 (2006.01)
Patent
CA 2567016
The present invention relates to a method for the preparation of a carboxylic imide having the general formula R1-(CO)-(NR3)-(CO)-R2~ (I), wherein a carboxylic anhydride having the general formula R1-(CO)-O-(CO)-R2~ (II) is reacted with urea or a urea derivative of the form (R3HN)-(CO)-(NR3H) in a solvent. In particular, the method can be used for the preparation of thalidomide.
Bonnier Hans
Landmesser Thomas
Oyen Wiggs Green & Mutala Llp
Siegfried Ltd.
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