A method for the preparation of dicarboxylic imides

Details A method for the preparation of dicarboxylic imides A method for the preparation of dicarboxylic imides

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) C07B 63/00 (2006.01) C07D 211/40 (2006.01)

Patent

CA 2567016

The present invention relates to a method for the preparation of a carboxylic imide having the general formula R1-(CO)-(NR3)-(CO)-R2~ (I), wherein a carboxylic anhydride having the general formula R1-(CO)-O-(CO)-R2~ (II) is reacted with urea or a urea derivative of the form (R3HN)-(CO)-(NR3H) in a solvent. In particular, the method can be used for the preparation of thalidomide.

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