"a method for the preparation of immunologically inert...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2442827

The present invention discloses a method for preparation of immunologically inert amniotic membranes using foetal membranes collected from programmed caesareans, under sterile conditions. The immunologically inert amniotic membrane of the invention may be applied to the preparation of a product to be used as a skin substitute in 2nd or 3rd degrees burns, as nerve sleeve to guide regeneration of the peripheral nerves, as cornea graft, in the reconstruction of the bladder and urethras, in the correction of cardiac malformations such as inter-auricular and inter-ventricular communications and in the reconstruction of valvular leaflets.

L'invention concerne un procédé de préparation de membranes amniotiques inertes sur le plan immunologique au moyen de membranes foetales recueillies lors de césariennes programmées, dans des conditions stériles. La membrane amniotique inerte sur le plan immunologique de l'invention s'utilise aussi dans la préparation d'un produit utilisé en tant que substitut de la peau lors de brûlures au deuxième ou au troisième degré, en tant que gaine nerveuse destinée à guider la régénération des nerfs périphériques, en tant que greffe de la cornée, dans la reconstruction de la vésicule et des urètres, dans la correction de malformations cardiaques telles que des communications interauriculaires ou interventriculaires et dans la reconstruction des valvules.

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