A method for the preparation of nucleic acid binding compound

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 473/16 (2006.01) C07D 239/46 (2006.01) C07D 473/18 (2006.01) C07D 473/34 (2006.01) C07D 487/04 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2228875

A method of the preparation of a nucleic acid binding compound is disclosed wherein a first protecting group removable by a medium strong base and a second protecting groupremovable by a medium strong acid are used. The synthesis is thereby is increased in recovery yield of a nucleic acid binding compound prepared.

On divulgue une méthode de préparation d'un composé se liant à un acide nucléique dans laquelle un premier groupe protecteur que l'on peut enlever à l'aide d'une base moyennement forte et un second groupe protecteur que l'on peut enlever à l'aide d'un milieu acide moyennement fort sont utilisés. Le rendement de la synthèse du composé se liant à un acide nucléique préparé est augmenté.

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