A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/475 (2006.01) C07K 14/71 (2006.01) C12N 15/16 (2006.01) C12N 15/17 (2006.01)
Patent
CA 2194366
The present invention relates generally to a method for the prophylaxis and/or treatment of skin disorders, and in particular proliferative and/or inflammatory skin disorders, and to genetic molecules useful for same. The present invention is particularly directed to genetic molecules capable of modulating growth factor interaction with its receptor on epidermal keratinocytes to inhibit, reduce or otherwise decrease stimulation of this layer of cells. The present invention contemplates, in a most preferred embodiment, a method for the prophylaxis and/or treatment of psoriasis.
L'invention concerne en général une méthode destinée à la prophylaxie et/ou au traitement d'affections de la peau, notamment prolifératives et/ou inflammatoires, ainsi que des molécules génétiques utilisées dans cette méthode. L'invention concerne en particulier des molécules génétiques pouvant moduler l'interaction du facteur de croissance avec son récepteur sur des kératinocytes épidermiques afin d'inhiber, réduire ou diminuer la stimulation de cette couche de cellules. Selon un mode de réalisation préférée, la présente invention concerne une méthode destinée à la prophylaxie et/ou au traitement du psoriasis.
Werther George Arthur
Wraight Christopher John
Murdoch Childrens Research Institute
Royal Children's Hospital Research Foundation
Smart & Biggar
LandOfFree
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