A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/30 (2006.01) A61P 17/02 (2006.01) A61P 17/06 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2376284
The present invention relates generally to a method for the prophylaxis and/or treatment of skin disorders, and in particular proliferative and/or inflammatory skin disorders, and to genetic molecules useful for same. The present invention is particularly directed to genetic molecules capable of modulating growth factor interaction with its receptor on epidermal keratinocytes to inhibit, reduce or otherwise decrease stimulation of this layer of cells. The present invention contemplates, in a most preferred embodiment, a method for the prophylaxis and/or treatment of psoriasis.
La présente invention concerne généralement une méthode de prophylaxie et/ou de traitement de troubles cutanés, et particulièrement de troubles cutanés inflammatoires et/ou proliférants, et des molécules génétiques utiles dans ces cas. Cette invention a notamment trait à des molécules génétiques capables de moduler l'interaction du facteur de croissance avec son récepteur sur des kératinocytes épidermiques pour inhiber, réduire ou diminuer la stimulation de cette couche des cellules. Dans un mode de réalisation préféré, elle porte sur une méthode de prophylaxie et/ou de traitement du psoriasis.
Werther George Arthur
Wraight Christopher John
Fetherstonhaugh & Co.
Murdoch Childrens Research Institute
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