C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/14 (2006.01) B01D 15/00 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2320190
For separating non-conventional transmissible agents (NCTAs), i.e. causative agent(s), of transmissible spongiform encephalopathies (TSEs) from a solution of a protein susceptible to contamination with NCTAs, particularly from blood products, at least one adsorbent is suspended, for a time of at least 10 minutes. The absorbent is selected from kieselguhr, diatomaceous earth, silicic acid, clay minerals, metal hydroxide, metal oxihydrate, cellulose, perlite, bentonite, and water- insoluble synthetic polymers. The obtained suspension is agitated, and subsequently the adsorbent is separated from the protein solution.
Pour la séparation d'agents transmissibles non conventionnels, c'est-à-dire le(s) agent(s) étiologique(s) d'encéphalopathies spongiformes transmissibles, d'une solution de protéine susceptible d'être contaminée par lesdits agents, notamment de produits sanguins, au moins un adsorbant est suspendu, pendant au moins 10 minutes. L'adsorbant est sélectionné parmi kieselguhr, la terre de diatomées, l'acide silicique, les argiles, l'hydroxyde de métal, l'oxyhydrate de métal, la cellulose, la perlite, la bentonite et des polymères synthétiques insolubles dans l'eau. La suspension obtenue est agitée, après quoi l'adsorbant est séparé de la solution protéique.
Maring Jacques-Andre
Morgenthaler Jean-Jacques
Rentsch Markus
Csl Behring Ag
Fetherstonhaugh & Co.
Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk
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