A method for the treatment of ocular oxidative stress

A - Human Necessities – 61 – K

Patent

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A61K 31/24 (2006.01) A61K 31/00 (2006.01) A61K 31/198 (2006.01) A61K 31/56 (2006.01) A61K 31/616 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61F 9/00 (2006.01) A61N 5/067 (2006.01)

Patent

CA 2350715

A method for combating the detrimental effects of oxidative stress on the eye involving the use of modifiers (both stimulators and/or inhibitors) of a fundamental nuclear regulatory mechanism in cells that controls both beneficial and detrimental aspects of oxidative stress produced by inflammation and other processes and the responses to these events in the eye. The ability to modulate nuclear wellness, aging and acute and chronic disease processes is achieved through regulation of NF.kappa.B controlled events, including the administration of one or more agents.

L'invention concerne un procédé destiné à combattre les effets nuisibles du stress oxydant sur l'oeil, qui implique l'utilisation des modificateurs (stimulants et/ou inhibiteurs) d'un mécanisme de régulation nucléaire fondamental dans des cellules qui commande les aspects bénéfiques et nuisibles du stress oxydant produit par des inflammations et d'autres processus, ainsi que les réactions à ces événements dans l'oeil. L'aptitude à moduler le mieux-être nucléaire, le vieillissement et les maladies chroniques et aiguës est obtenue grâce à la régulation d'événements commandés par le facteur nucléaire NF.kappa.B, y compris l'administration d'au moins un agent.

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