A method for the treatment, prevention, or inhibition of a...

Details A method for the treatment, prevention, or inhibition of a... A method for the treatment, prevention, or inhibition of a...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/10 (2006.01) A61K 31/137 (2006.01) A61K 31/138 (2006.01) A61K 31/18 (2006.01) A61K 31/196 (2006.01) A61K 31/353 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/382 (2006.01) A61K 31/4164 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/47 (2006.01) A61K 31/4745 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61K 31/519 (2006.01) A61K 31/53

Patent

CA 2508884

A method of treating, preventing, or inhibiting a CNS disorder and/or pain and inflammation or an inflammation-associated disorder in a subject in need of such treatment or prevention provides for treating the subject with duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor or prodrug thereof, wherein the amount of duloxetine, venlafaxine or atomoxetine and the amount of a cyclooxygenase-2 selective inhibitor or prodrug thereof together constitute a CNS disorder, pain and inflammation, or inflammation-associated disorder suppressing treatment, prevention, or inhibition effective amount of the composition. Compositions and pharmaceutical compositions that contain duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor are also disclosed.

L'invention concerne une méthode de traitement, de prévention ou d'inhibition d'un trouble du SNC et/ou de la douleur ou d'une inflammation, ou d'un trouble associé à une inflammation, chez un sujet nécessitant un tel traitement ou une telle prévention. La méthode consiste à traiter le sujet avec de la duloxetine, de la venlafaxine ou de l'atomoxetine, et avec un inhibiteur sélectif de la cyclo-oxygénase-2 ou son promédicament. La quantité de duloxetine, de venlafaxine ou d'atomoxetine et la quantité de l'inhibiteur sélectif de la cyclo-oxygénase-2 ou son promédicament constituent ue quantité efficace de la composition pouvant guérir, prévenir ou inhiber un trouble du SNC, la douleur ou une inflammation, ou un trouble associé à une inflammation. L'invention concerne en outre des compositions et des compositions pharmaceutiques contenant de la duloxetine, de la venlafaxine ou de l'atomoxetine et un inhibiteur sélectif de la cyclo-oxygénase-2.

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