A method for tumor treatment with fumagillol derivatives

Details A method for tumor treatment with fumagillol derivatives A method for tumor treatment with fumagillol derivatives

A - Human Necessities

61

K

A61K 31/336 (2006.01) A61K 31/17 (2006.01) A61K 31/337 (2006.01) A61K 31/7068 (2006.01) A61K 45/06 (2006.01) A61K 45/08 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2381829

38 A method of and a kit for treating a tumor by administering a therapeutically-effective amount of a fumagillol derivative and at least one antineoplastic agent to a patient in need of such treatment is disclosed. A presently preferred treatment is to administer 6-O-(N-chloroacetylcarbamoyl) fumagillol and paclitaxel. A method of and a kit for treating a tumor by administering a therapeutically-effective amount of a fumagillol derivative, at least one platinum complex and at least one other antineoplastic agent to a patient in need of such treatment is also disclosed. A presently preferred treatment is to administer 6-O-(N-chloroacetylcarbamoyl) fumagillol, carboplatin and paclitaxel.

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