A method for using lipoprotein associated coagulation...

Details A method for using lipoprotein associated coagulation... A method for using lipoprotein associated coagulation...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 38/57 (2006.01) A61K 39/40 (2006.01)

Patent

CA 2136953

A method for prophylactically or therapeutically treating sepsis or septic shock is described, wherein an inhibitor to tissue factor is administered to septic patients. Additionally, a method for treating inflammation is described wherein the inhibitor is administered to patients. This inhibitor is termed lipoprotein associated coagulation inhibitor, or commonly LACI. It is 38 kD and has 276 amino acids. LACI has now been shown to be useful for the treatment of sepsis, septic shock and inflammation.

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