A method of administering a pde3 inhibitor via titration for...

Details A method of administering a pde3 inhibitor via titration for... A method of administering a pde3 inhibitor via titration for...

A - Human Necessities

61

K

A61K 31/501 (2006.01)

Patent

CA 2714160

The present invention includes a method of administering a type III phosphodiesterase (PDE3) inhibitor via titration. For example, the method comprises administering to a mammal multiple doses of the PDE3 inhibitor, wherein one or more doses are administered in an initial dosage amount and one or more doses are subsequently administered in an end dosage amount, and the initial dosage amount is less in amount than the end dosage amount. Preferably, the PDE3 inhibitor is also a TXA2 synthase inhibitor.

L'invention concerne un procédé d'administration d'un inhibiteur de phosphodiestérase de type III (PDE3) par titrage. Par exemple, le procédé comprend l'administration à un mammifère de multiples doses de l'inhibiteur de PDE3, une ou plusieurs doses étant administrées dans une quantité posologique initiale et une ou plusieurs doses étant administrées ultérieurement dans une quantité posologique finale, et la quantité posologique initiale étant inférieure à la quantité posologique finale. De préférence, l'inhibiteur de PDE3 est également un inhibiteur de TXA2 synthase.

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