A method of assaying for agonists or antagonist of dynorphin...

Details A method of assaying for agonists or antagonist of dynorphin... A method of assaying for agonists or antagonist of dynorphin...

G - Physics

01

N

G01N 33/566 (2006.01) C07K 14/665 (2006.01) C07K 14/72 (2006.01) G01N 33/50 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2430719

The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of Dynorphin A and its analogues. The assays are based upon the binding of Dynorphin A and its analogues to the rat and human MAS receptors.

L'invention concerne des dosages biologiques qui permettent de s~lectionner des compos~s agissant comme agonistes, antagonistes ou agonistes inverses de la dynorphine A et de ses analogues. Ces dosages biologiques s'appuient sur la liaison de la dynorphine A et de ses analogues aux r~cepteurs MAS du rat et des humains.

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