A method of controlling fungal pathogens, and agents useful...

A - Human Necessities – 01 – N

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A01N 63/00 (2006.01) A01H 5/00 (2006.01) A01N 37/36 (2006.01) A01N 37/42 (2006.01) A01N 63/02 (2006.01) C12N 9/04 (2006.01) C12N 15/53 (2006.01) C12N 15/82 (2006.01) C12P 7/58 (2006.01) C12P 7/60 (2006.01)

Patent

CA 2360600

A method of preventing or treating infection by a range of fungal pathogens in an animal or plant or stored plant product comprising administering an effective amount of a sugar acid, in particular mannonic acid, gluconic acid or galacturonic. The sugar acid can be delivered by a biocontrol that can manufacture the sugar acid. An exemplified biocontrol is Pseudomonas strain AN5, which is characterized by the capacity to convert aldose to sugar acid. Also disclosed are nucleotide sequences from enzymes in the Pseudomonas PQQ enzyme pathway which may be used to transform microorganisms and plants so that they produce sugar acids at levels sufficient to control the growth or viability of pathogens.

Cette invention se rapporte à un procédé servant à prévenir ou à traiter les infections causées par une large gamme de pathogènes fongiques dans un organisme animal ou une plante ou un produit végétal entreposé et consistant à cet effet à administrer une quantité efficace d'un acide de sucre, en particulier de l'acide mannonique, de l'acide gluconique ou galacturonique. Cet acide de sucre peut être libéré par un agent de lutte biologique ayant la capacité de fabriquer cet acide de sucre. Un exemple d'agent de lutte biologique est fourni par la souche de Pseudomonas AN5, qui se caractérise par sa capacité à convertir l'aldose en acide de sucre. Cette invention concerne également des séquences nucléotidiques tirées d'enzymes dans le canal enzymatique PQQ de Pseudomonas, qui peuvent servir à transformer des microorganismes et des plantes en vue de leur faire produire des acides de sucre à des niveaux suffisants pour limiter la croissance ou la viabilité des pathogènes.

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