A method of controlling the temperature of a specimen in or...

G - Physics – 01 – N

Patent

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Details

G01N 1/44 (2006.01) B01L 3/00 (2006.01) B01L 7/00 (2006.01) G02B 21/34 (2006.01)

Patent

CA 2376969

The invention relates to a method of controlling the temperature of a specimen by using induction heating. The specimen is either fixed to a carrier or is in liquid form in contact with a carrier with fixed capture probes. The carrier is removably placed in, on, or under a support member comprising a conducting material, and the method comprising a step of subjecting the solid support to an oscillating magnetic field. The invention also relates to the solid support member in combination with a carrier and the use of it. The specimen is preferably a biological specimen and the carrier and support member are preferably a microscope slide and a cartridge, respectively. In a second aspect, the invention relates to a method of controlling the temperature of a specimen or a capture probe for a specimen fixed onto micro beads, said beads being sufficiently small to be flowable in a liquid fluid, preferably water or a specimen in liquid form. The beads comprise electrically conducting material and are placed in a liquid, and the method includes the step of carrying the micro beads through an oscillating magnetic field for generating heat.

L'invention concerne un procédé permettant de réguler la température d'un échantillon par utilisation d'un chauffage à induction. Cet échantillon est soit fixé à un support, soit sous forme liquide et en contact avec un support pourvu de sondes de capture fixes. Ledit support est placé amovible dans un élément porteur comprenant un matériau de conduction, sur ledit élément porteur, ou en-dessous de celui-ci. Le procédé consiste à soumettre cet élément porteur solide à un champ magnétique oscillant. L'invention concerne également un élément porteur solide associé à un support, et son utilisation. L'échantillon est de préférence un échantillon biologique, et l'élément porteur et le support sont respectivement, de préférence, une lame de microscope et une cartouche. Selon un second aspect, l'invention concerne un procédé permettant de réguler la température d'un échantillon, ou d'une sonde de capture destinée à cet échantillon fixée sur des micro-billes, lesdites micro-billes étant suffisamment petites pour être en suspension dans un fluide liquide, de préférence, de l'eau ou un échantillon sous forme liquide. Ces billes comprennent un matériau électro-conducteur, et sont placées dans un liquide. Le procédé consiste à faire passer les micro-billes à travers un champ magnétique oscillant de façon à produire de la chaleur.

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