G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2229187
A method of determining the degree of aggregation of the .beta.A4 peptide is disclosed. The method comprises reacting the protein with a suitable binding agent which is capable of binding the .beta.A4 peptide only in its non- aggregated state to form an amount of protein bound binding reagent. The amount of protein bound binding agent is then measured.
L'invention porte sur un procédé permettant de déterminer le degré d'agrégation du peptide .beta.A4 consistant à faire réagir la protéine avec un agent de fixation adéquat ne pouvant fixer le peptide .beta.A4 qu'à l'état non agrégé pour former une quantité de réactif de fixation fixé à la protéine. On peut ainsi mesurer la quantité d'agent de fixation fixé à la protéine.
Goyal Shefali
Paul Joseph West
Riedel Norbert G.
Sahasrabudhe Sudhir R.
Aventis Pharmaceuticals Inc.
Hoechst Marion Roussel Inc.
Osler Hoskin & Harcourt Llp
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