A method of forming and the resulting membrane composition...

A - Human Necessities – 61 – L

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A61L 31/14 (2006.01) A61L 31/04 (2006.01) A61L 31/18 (2006.01)

Patent

CA 2748337

A method of forming and the resulting membrane composition for securement to a patient's bone or tissue to reduce the formation of tissue adhesions following a surgical procedure comprises a first component and a second component. The first component comprises a hydrogel including at least one crosslinked polymer. The second component comprises a textile component. The composition has a thickness between about two tenths of a millimeter (0.2 mm) to about six tenths of a millimeter (0.6 mm), a suture retention strength between about one Newton (1 N) to about thirteen Newtons (13 N), a static coefficient of friction between about one hundredth (0.01) and about one-half (0.5), a kinetic coefficient of friction between about one hundredth (0.01) and about one-half (0.5) and a flexibility of less than thirty millimeters (30 mm) bend length. A method of reducing the occurrence of tissue adhesions following surgery comprises applying the membrane composition to a surgical site.

L'invention porte sur un procédé de formage et sur la composition membranaire résultante destinée à être fixée à l'os ou au tissu d'un patient afin de réduire la formation d'adhérences tissulaires à la suite d'une opération chirurgicale, lequel procédé comprend un premier composant et un second composants. Le premier composant comprend un hydrogel comprenant au moins un polymère réticulé. Le second composant comprend un composant textile. La composition a une épaisseur comprise entre environ deux dixièmes de millimètre (0 ,2 mm) et environ six dixièmes de millimètre (0,6 mm), une résistance à la rétention de suture comprise entre environ un Newton (1 N) et environ treize Newtons (13 N), un coefficient de frottement statique compris entre environ un centième (0,01) et environ un demi (0,5), un coefficient de frottement cinétique compris entre environ un centième (0,01) et environ un demi (0,5) et une flexibilité inférieure à une longueur de courbure de trente millimètres (30 mm). Le procédé de réduction de l'apparition d'adhésion tissulaire à la suite d'une chirurgie comprend l'application de la composition de membrane à un site chirurgical.

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