C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) A61K 39/00 (2006.01) C07K 1/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/12 (2006.01)
Patent
CA 2317029
This invention relates to new vaccines against microorganisms based on antigenically mimetic peptides. The invention also relates to methods of discovering such mimetic peptides by first screening peptide-display phage libraries with antibodies against the microbial carbohydrate(s) of interest to locate antigenically mimetic peptides. Vaccines against Group B Streptococcus, or Streptococcus Agalactiae, are preferably produced using this method.
Cette invention concerne de nouveaux vaccins contre des micro-organismes, vaccins qui font appel à des peptides qui sont des mimétiques antigéniques. La présente invention concerne également des procédés mis en oeuvre pour la recherche de tels peptides mimétiques. Ces procédés consistent dans un premier temps à effectuer des criblages de banques de phages affichant ces peptides au moyen d'anticorps dirigés contre les glucides microbiens d'intérêt afin de localiser des peptides mimétiques antigéniques. On utilisera de préférence cette technique pour la fabrication de vaccins contre les streptocoques du groupe B ou Streptococcus Agalactiae.
Kirby Eades Gale Baker
Montana State University
Pincus Seth H.
LandOfFree
A method of isolating a peptide which immunologically mimics... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method of isolating a peptide which immunologically mimics..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method of isolating a peptide which immunologically mimics... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1840028