A method of magnetic resonance focused surgical and...

A - Human Necessities – 61 – B

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A61B 5/055 (2006.01) A61K 49/18 (2006.01) A61K 49/22 (2006.01) A61N 7/00 (2006.01) G01R 33/28 (2006.01) G01R 33/561 (2006.01)

Patent

CA 2214855

A novel method of magnetic resonance focused surgical ultrasound by administering to a patient a magnetic resonance imaging (MRI) contrast medium comprising gas filled vesicles, then scanning the patient with MRI techniques, and then applying ultrasound to effect surgery. These methods may also use an MRI contrast medium comprising gaseous precursor filled vesicles which undergo a phase transition from a liquid to gas in vivo after administration. Additionally, the MRI contrast medium may comprise a therapeutic compound.

Cette invention concerne un nouveau procédé de traitement chirurgical aux ultrasons dirigés par résonance magnétique consistant à administrer à un patient un milieu de contraste pour imagerie par résonance magnétique (IRM), ledit milieu contenant des vésicules remplies de gaz, à procéder ensuite à la scintigraphie du patient au moyen des techniques d'IRM et à pratiquer ensuite la chirurgie par ultrasons. On peut également utiliser avec ces procédés un milieu de contraste pour IRM comportant des vésicules remplies de précurseurs gazeux qui subissent un changement de phase de l'état liquide à l'état gazeux, in vivo, après l'administration. En outre, ce milieu de contraste pour IRM peut comporter un composé thérapeutique.

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