A method of modulating an immune response in an infected...

A - Human Necessities – 61 – K

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Details

A61K 39/29 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 31/557 (2006.01) A61K 31/655 (2006.01) A61K 35/66 (2006.01) A61K 38/13 (2006.01) A61K 38/16 (2006.01) A61K 39/385 (2006.01) A61P 31/00 (2006.01) C12N 15/82 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2276450

Methods and compositions for modulating an immune response in a mammal infected with a bacterium, a virus, or a parasite are provided. The methods and compositions are useful in mammals experiencing an acute infection and in mammals experiencing a chronic infection. The methods and compositions may be used in conjunction with a known treatment for infection of a mammal by an infectious agent. Methods and compositions for transmucosal delivery of a molecule comprising an epitope located in close proximity to the immune response are provided.

L'invention concerne des procédés et des compositions qui permettent de moduler une réaction immunitaire chez un mammifère infecté par une bactérie, un virus ou un parasite. Lesdits procédés et compositions conviennent pour des mammifères atteints d'une infection aiguë ou pour des mammifères atteints d'une infection chronique. Lesdits procédés et compositions peuvent être utilisés en combinaison avec un traitement classique administré à un mammifère infecté par un agent infectieux. L'invention concerne également des procédés et des compositions servant à l'émission transmuqueuse d'une molécule contenant un épitope situé à proximité immédiate de la réaction immunitaire.

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