A method of modulating cellular activity and molecules for...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 38/04 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61P 37/02 (2006.01) C07K 7/02 (2006.01) C07K 14/74 (2006.01)

Patent

CA 2497833

The present invention relates generally to a method of modulating T cell functional activity by utilising .beta.-amino acid substituted peptides and to agents useful for the same. More particularly, the present invention relates to a method of modulating class I restricted T cell activity by utilising .beta.-amino acid substituted peptides and to agents useful for the same. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by suboptimal T cell stimulation such as that which occurs in some viral infections and in anti-tumour immunity, as well as aberrant, unwanted or otherwise inappropriate T cell functioning such as, but not limited to, graft rejection or autoimmune conditions, the present invention is further directed to methods of identifying, designing and/or modifying agents capable of modulating T cell functional activity.

La présente invention concerne, en général, une méthode de modulation de l'activité fonctionnelle de lymphocytes T au moyen de peptides substitués par des acides aminés .beta., et des agents destinés à cette méthode. Plus particulièrement, cette invention a trait à une méthode de modulation de l'activité de lymphocytes T restreinte de classe I au moyen desdits peptides substitués par des acides aminés .beta., et à des agents associés. La méthode de l'invention est utilisée, inter alia, dans le traitement et/ou la prophylaxie de troubles caractérisés par une stimulation des lymphocytes T sous-optimale, telle que celle qui se produit dans certaines infections virales et dans l'immunité anti-tumorale, ainsi que dans le fonctionnement de lymphocytes T aberrant, non souhaité ou inapproprié, mais également dans le cas de rejet de greffe ou de troubles auto-immuns. Ladite invention a aussi pour objet des méthodes d'identification, de conception et/ou de modification d'agents capables de moduler l'activité fonctionnelle de lymphocytes T.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

A method of modulating cellular activity and molecules for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A method of modulating cellular activity and molecules for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method of modulating cellular activity and molecules for... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1414562

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.