A method of modulating ion channel functional activity

Details A method of modulating ion channel functional activity A method of modulating ion channel functional activity

A - Human Necessities

61

K

A61K 31/4965 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2345896

The present invention relates generally to a method of retarding, reducing or otherwise inhibiting viral functional activity and, more particularly, to a method of reducing, retarding or otherwise inhibiting viral functional activity by down-regulating Vpu ion channel functional activity. Even more particularly, the present invention provides a method of treating HIV infection or AIDS by inhibiting Vpu ion channel mediated HIV replication.

La présente invention concerne globalement un procédé permettant de retarder, de réduire ou d'inhiber de tout autre manière l'activité fonctionnelle virale et, plus particulièrement, un procédé permettant de réduire, de retarder ou d'inhiber de tout autre manière l'activité fonctionnelle virale au moyen de la régulation à la baisse de l'activité fonctionnelle du canal ionique Vpu. De manière encore plus particulière, la présente invention concerne un procédé de traitement de l'infection par VIH ou du SIDA au moyen de l'inhibition de la réplication du VIH induite par le canal ionique Vpu.

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