A method of modulating the activity of a nucleic acid molecule

Details A method of modulating the activity of a nucleic acid molecule A method of modulating the activity of a nucleic acid molecule

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) A61K 38/43 (2006.01)

Patent

CA 2682580

The present invention relates, in general, to agents that modulate the pharmacological activity of nucleic acid molecules and, in particular, to agents that bind therapeutic or diagnostic nucleic acid molecules in a sequence independent manner and modulate (e.g., inhibit or reverse) their activity. The invention also relates to compositions comprising such agents and to methods of using same.

De manière générale, la présente invention concerne des agents qui modulent l'activité pharmacologique des molécules d'acides nucléiques et, en particulier, des agents qui se lient à des molécules d'acides nucléiques thérapeutiques ou diagnostiques d'une manière indépendante de la séquence et modulent (par exemple, inhibent ou inversent) leur activité. L'invention concerne également des compositions comprenant ces agents et des procédés pour les utiliser.

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