A method of producing a factor viii preparation

Details A method of producing a factor viii preparation A method of producing a factor viii preparation

C - Chemistry, Metallurgy

07

K

C07K 14/755 (2006.01) A61K 35/14 (2006.01) A61K 38/37 (2006.01) A61L 2/06 (2006.01) A61L 2/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094347

The invention relates to a method of producing virus-safe highly purified factor VIII. The method includes a combination of the following measures: a) chromatographic purification of a factor VIII- containing fraction, b) tenside treatment of factor VIII in an aqueous solution at a tenside/protein ration of from 1:1 to 1000:1, and c) heat treatment of the factor VIII preparation in the solid state.

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