A method of producing porous microparticles

Details A method of producing porous microparticles A method of producing porous microparticles

A - Human Necessities

61

K

A61K 9/16 (2006.01)

Patent

CA 2640165

A method of preparing porous microparticles comprises the steps of combining one or more organic compounds with a volatile system, and drying the system thus formed to provide substantially pure porous microparticles of the organic compound or composite porous microparticles of combinations of organic compounds. Organic compounds used in the method may be one or more of a bioactive, a pharmaceutically acceptable excipient, a pharmaceutically acceptable adjuvant or combinations thereof. The invention also relates to porous microparticles produced by such a method, and pharmaceutical compositions comprising such porous microparticles.

La présente invention concerne un procédé de préparation de microparticules poreuses comprenant les étapes de combinaison d~un ou plusieurs composés organiques avec un système volatile et le séchage du système ainsi formé afin de fournir des microparticules poreuses sensiblement pures du composé organique ou des particules poreuses composites de combinaisons de composés organiques. Les composés organiques utilisés dans ce procédé pourront être : composé bioactif et/ou excipient et/ou adjuvant pharmaceutiquement acceptable, ou leurs combinaisons. L~invention a aussi trait à des microparticules poreuses produites par un tel procédé et à des compositions pharmaceutiques comprenant de telles microparticules poreuses.

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