A method of purifying sodium hyaluronate

Details A method of purifying sodium hyaluronate A method of purifying sodium hyaluronate

C - Chemistry, Metallurgy

08

B

C08B 37/08 (2006.01) C12P 19/26 (2006.01)

Patent

CA 2232785

Highly purified sodium hyaluronate having a low content of pyrogen is obtained by adding a salt and a water-soluble organic solvent to a solution containing sodium hyaluronate, or to a sodium hyaluronate solution previously filtered through a positively charged filter, precipitating and sedimenting the sodium hyaluronate and taking out a supernatant to remove pyrogen. 23

Il est possible d'obtenir un hyaluronate de sodium hautement purifié contenant peu de pyrogène en ajoutant un sel et un solvant organique hydrosoluble à une solution contenant du hyaluronate de sodium ou à une solution de hyaluronate de sodium auparavant filtrée à travers un filtre positivement chargé, dans laquelle le hyaluronate de sodium a été précipité et sédimenté et dont le surnageant a été retiré pour enlever le pyrogène.

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