C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 253/075 (2006.01) G01N 33/15 (2006.01) G01N 30/02 (2006.01) G01N 30/90 (2006.01)
Patent
CA 2265194
A method of testing the purity or stability to degradation of a sample of lamotrigine (IV) or a pharmaceutical dosage form comprising lamotrigine which comprises assaying the said sample for the presence of a compound selected from 3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazine-5-(4H)-one (compound A) and N-[5-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide (compound B). A process for producing compound B, which is novel, is also disclosed. (see formula (IV) (see formula (A) (see formula (B)
Edmeades Lorraine Mary
Griffith-Skinner Nigel Arthur
Hill Derek Anthony
Hill Graham Thronton
Packham Terence William
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Wellcome Foundation Limited
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