C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/06 (2006.01) A61K 39/12 (2006.01) A61K 39/21 (2006.01) A61K 39/29 (2006.01) C12N 7/02 (2006.01)
Patent
CA 2412503
The present invention relates to a method for reducing the occurrence and severity of infectious diseases, especially infectious diseases in which lipid- containing infectious organisms are found in biological fluids, such as blood. The present invention employs solvents useful for extracting lipids from the lipid-containing infectious organism, thereby reducing the infectivity of the infectious organism. The present invention also provides a vaccine composition, comprising a lipid-containing infectious organism, treated with solvents to reduce the lipid content of the infectious organism, combined with a pharmaceutically acceptable carrier. The vaccine composition is administered to an animal or a human to provide protection against the lipid-containing infectious organism.
La présente invention concerne une méthode qui permet de diminuer la survenue et la gravité de maladies infectieuses, notamment de maladies infectieuses dans lesquelles des organismes infectieux contenant des lipides sont présents dans des fluides biologiques, tels que le sang. La méthode de l'invention met en oeuvre des solvants pouvant extraire les lipides des organismes infectieux contenant des lipides. L'invention concerne en outre une composition vaccinale, associée à un support pharmaceutiquement acceptable, qui comprend un organisme infectieux contenant des lipides traité avec des solvants afin de réduire le taux de lipides chez l'organisme infectieux. La composition vaccinale est administrée à un animal ou un humain pour le protéger contre l'organisme infectieux contenant des lipides.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Eli Lilly And Company
Lipid Sciences Inc.
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