A method of treating cancer

Details A method of treating cancer A method of treating cancer

A - Human Necessities

01

N

A01N 43/42 (2006.01) A01N 43/60 (2006.01) A61K 31/195 (2006.01) A61K 31/223 (2006.01) A61K 31/365 (2006.01) A61K 31/4164 (2006.01) A61K 31/4184 (2006.01) A61K 31/425 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2286239

The present invention relates to methods of treating cancer using a combination of a compound which is an integrin antagonist and a compound which is an inhibitor of farnesyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is an integrin antagonist and a compound which is an inhibitor of farnesyl-protein transferase. The invention also relates to methods of preparing such compositions.

L'invention concerne des procédés de traitement du cancer visant à utiliser en combinaison un composé antagoniste de l'intégrine et un composé inhibiteur de farnésyl transférase, lesdits procédés consistant à administrer à un mammifère, de manière séquentielle dans un ordre indéterminé ou simultanément, des quantités d'au moins deux agents thérapeutiques choisis dans un groupe comprenant un composé antagoniste de l'intégrine et un composé inhibiteur de farnésyle transférase. L'invention concerne aussi des procédés qui permettent d'élaborer les compositions considérées.

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