A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/45 (2006.01) A61K 31/133 (2006.01) A61K 31/277 (2006.01) A61K 31/352 (2006.01) A61K 31/4045 (2006.01) A61K 38/16 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2595469
The present invention relates generally to a method of modulating hyperglycaemia-induced endothelial cell functioning and agents useful for same. More particularly, the present invention relates to a method of modulating hyperglycaemia-induced vascular endothelial cell functioning by modulating intracellular sphingosine kinase-mediated signalling. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of the adverse vascular endothelial cell functioning associated with conditions characterised by hyperglycaemia, and/or diabetes mellitus, per se.
L'invention concerne, d'une manière générale, un procédé de modulation du fonctionnement cellulaire endothélial induit par l'hyperglycémie et des agents utiles pour cela. Plus précisément, l'invention concerne un procédé de modulation du fonctionnement cellulaire endothélial vasculaire induit par l'hyperglycémie consistant à moduler la signalisation induite par la sphingosine kinase intercellulaire. Le procédé selon l'invention est utile, inter alia, dans le traitement et/ou la prophylaxie du fonctionnement cellulaire endothélial vasculaire indésirable associé à des états caractérisés par l'hyperglycémie et/ou le diabète, per se.
Vadas Mathew Alexander
Wang Lijun
Xia Pu
Medvet Science Pty. Ltd.
Smart & Biggar
LandOfFree
A method of treating cellular damage does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method of treating cellular damage, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method of treating cellular damage will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1388951