A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) C07D 211/90 (2006.01) C07D 239/22 (2006.01)
Patent
CA 2442455
The invention provides a method for treating a condition via modulation of the Eg5 protein activity comprising administering to a mammalian species in need of such treatment an effective amount of at least one small molecule Eg5 protein inhibitor. The invention also provides a method for treating a condition via modulation of the Eg5 protein activity comprising administering to a mammalian species in need of such treatment an effective amount of at least one small molecule Eg5 protein inhibitor in combination with at least one other anti-cancer agent.
Cette invention concerne une méthode de traitement d'une maladie par modulation de l'activité de la protéine Eg5, qui consiste à administrer à une espèce mammifère qui en a besoin une dose efficace d'au moins un inhibiteur de protéine Eg5 à petite molécule. L'invention concerne également une méthode consistant à administrer à une espèce mammifère qui en a besoin une dose efficace d'au moins un inhibiteur de protéine Eg5 à petite molécule en combinaison avec un autre agent anti-cancéreux.
Kimball Spencer David
Lombardo Louis J.
Rawlins David B.
Roussell Deborah L.
Xiao Hai-Yun
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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