A method of treating substance addiction

Details A method of treating substance addiction A method of treating substance addiction

A - Human Necessities

61

K

A61K 31/553 (2006.01) A61K 31/277 (2006.01) A61K 31/4422 (2006.01) A61K 31/485 (2006.01) A61P 25/32 (2006.01) A61P 25/36 (2006.01)

Patent

CA 2390101

The present invention relates to methods of therapy for substance addiction comprising the administration of a combination of µ-opioid receptor antagonist and a calcium channel blocker which is long lasting or in a sustained release form, said calcium channel blocker selected from verapamil, nifedipine, amlodipine and felodipine, as well as combinations and compositions useful therefor.

Cette invention se rapporte à des procédés de thérapie de l'accoutumance aux substances intoxiquantes, qui consistent à administrer une combinaison d'un antagoniste des récepteurs de µ-opioïdes et un inhibiteur des canaux calciques, qui se présente sous une forme durable ou sous une forme à libération soutenue, et qui est choisi parmi vérapamil, nifédipine, amlodipine et félodipine, ainsi qu'à des combinaisons et des compositions utiles dans ces procédés.

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