A method of treating tumors with azaxanthones

C - Chemistry – Metallurgy – 07 – D

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C07D 491/052 (2006.01) A61K 31/436 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2633112

The use of azaxanthones for treating diseases associated with tumor cells which express one or more protein of S100 family, and in treating patients that have malignancies consisting of tumors of an epithelial or mesenchymel nature, where these compounds are effective in retarding the progression and/or metastasis of these tumors.

La présente invention concerne l'utilisation d'azaxanthones pour le traitement de maladies associées aux cellules tumorales qui expriment une ou plusieurs protéines de la famille S100, et pour le traitement de patients qui souffrent de malignités constituées par les tumeurs de nature épithéliale ou mésenchymateuse, ces composés étant efficaces pour retarder la progression et/ou la métastase de ces tumeurs.

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