A method of treatment of the dental pulp and filling root...

A - Human Necessities – 61 – K

Patent

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A61K 6/00 (2006.01)

Patent

CA 2677745

Improved compositions comprising a mixture of particulate materials with water-based liquids containing water-soluble polymers and surfactants are provided. Examples of particulate powders include mixtures of calcium silicate, calcium aluminate, calcium sulfate, and hydroxyapatite. Examples of water-soluble polymers include polyvinyl alcohols, polyvinyl pyrrolidone, partially hydrolyzed polyvinyl acetates, polyacrylic acid, and polymethacrylic acid. Surfactants such as sodium dodecyl sulfate are added to the composition to interact with the polymeric materials. The compositions are particularly suitable for sealing and obturating dental root canals and root apices. The composition provides a stable barrier to bacterial' and fluid leakage in the root canal system of a tooth. In addition, the compositions help promote the growth of new bone and tissue surrounding the root-tip area or dentin tissue that covers an injured or amputated pulp.

L'invention concerne des compositions améliorées comprenant un mélange de matériaux particulaires avec des liquides à base d'eau contenant des polymères hydrosolubles et des agents tensioactifs. Des exemples de poudres particulaires comprennent des mélanges de silicate de calcium, d'aluminate de calcium, de sulfate de calcium et d'hydroxyapatite. Les exemples de polymères hydrosolubles comprennent les poly(alcools vinyliques), la poly(vinyl pyrrolidone), les poly(acétates de vinyle) partiellement hydrolysés, le poly(acide acrylique) et le poly(acide méthacrylique). Les agents tensioactifs tels que le dodécylsulfate de sodium sont ajoutés à la composition pour interagir avec les matériaux polymères. Les compositions sont particulièrement appropriées pour l'étanchéité et l'obturation des canaux radiculaires dentaires et des apex de la racine. La composition assure une barrière stable vis-à-vis des bactéries et des fuites de fluide dans le système de canal radiculaire d'une dent. De plus, les compositions permettent de favoriser la croissance osseuse et le développement du tissu entourant la zone d'extrémité de racine ou le tissu de dentine qui recouvre une pulpe lésée ou amputée.

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