A method to produce succinic acid from raw hydrolysates

C - Chemistry – Metallurgy – 12 – P

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C12P 1/00 (2006.01) C12N 1/20 (2006.01) C12P 7/00 (2006.01) C12P 7/46 (2006.01) C12P 7/64 (2006.01)

Patent

CA 2565727

A method for producing succinic acid from industrial-grade hydrolysates uses an organism that contains mutations for the genesptsG, pflB, and ldhA, and allows the organism to accumulate biomass, and allow s the organism to metabolize the hydrolysate. A bacteria mutant produces succinic acid from substrate contained in industrial-grade hydro-lysate in a ratio of between 0.6:1 and 1.3:1 succinic acid to substrate.

Un procédé de fabrication d'acide succinique à partir d'hydrolysats de niveau industriel utilise un organisme qui contient des mutations pour les gènes ptsG, pflB, et ldhA, et permet aux organismes d'accumuler de la biomasse, tout comme il permet à l'organisme de métaboliser l'hydrolysat. Un mutant de bactéries produit de l'acide succinique à partir du substrat contenu dans l'hydrolysat de niveau industriel dans un rapport compris entre 0,6 sur 1 et 1,3 sur 1 d'acide succinique sur substrat.

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