A methodology of estimating the conformation of a protein by...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2503626

The invention relates to a method for determining the effect of a polymorphism or mutation on the structural properties of a protein wherein the method relies on the structural properties of the protein and so its cleavage during proteolysis.

La présente invention concerne un procédé qui permet de déterminer l'effet d'un polymorphisme ou d'une mutation sur les propriétés structurelles d'une protéine, ledit procédé reposant sur les propriétés structurelles de la protéine, et par conséquent sur le clivage de cette dernière, au cours de la protéolyse.

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