A microchip electrospray device and column with affinity...

B - Operations – Transporting – 01 – D

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B01D 15/08 (2006.01) B01J 45/00 (2006.01) G01N 30/72 (2006.01) H01J 49/04 (2006.01) B01D 15/38 (2006.01) G01N 30/46 (2006.01) G01N 30/52 (2006.01) G01N 30/60 (2006.01)

Patent

CA 2438247

A microchip-based electrospray ionization device and column with affinity adsorbents is disclosed. The invention includes a microchip array.(2) and a capillary tube (1) or alone or attached in combination. At least a portion of the device or column has immobilized affinity adsorbents. Methods for using the device are provided as well for affinity capture of biomolecules to meet the needs for the modern life sciences such as proteomics and drug discover.

L'invention concerne un dispositif d'ionisation à micropuce et une colonne comprenant des adsorbents d'affinité. L'invention comprend un réseau (2) de micropuces et un tube capillaire (1) seul ou combiné. Au moins une partie du dispositif ou de la colonne comprend des adsorbents d'affinité fixes. L'invention concerne également des méthodes d'utilisation du dispositif pour la capture par affinité de biomolécules afin de répondre aux besoins des sciences de la vie moderne, par exemple la protéomique et la découverte de médicaments.

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