A model biofilm for efficacy assessment of antimicrobials

C - Chemistry – Metallurgy – 12 – M

Patent

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C12M 1/26 (2006.01)

Patent

CA 2376372

A method for growing a model biofilm is disclosed. In one embodiment, the method comprises the steps of placing a plurality of surfaces comprising a top and a bottom on an inoculated growth medium (wherein the growth medium is in contact with a nutrative source), growing a model biofilm on the bottom of the plurality of surfaces, and removing the surfaces from the growth medium, wherein a model biofilm is coated onto the bottom of the surface.

Cette invention se rapporte à un procédé servant à faire croître un biofilm modèle. Dans un mode de réalisation, ce procédé consiste à placer plusieurs surfaces comprenant une partie supérieure et une partie inférieure sur un support de croissance inoculé, ce support de croissance étant en contact avec une source nutritive, à faire croître un biofilm modèle sur la partie inférieure de ces surfaces, et à retirer lesdites surfaces du support de croissance, de telle sorte qu'un biofilm modèle se trouve déposé sous la forme de revêtement sur la partie inférieure de ladite surface.

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