A molecular prognostic signature for predicting breast...

C - Chemistry – Metallurgy – 40 – B

Patent

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C40B 40/06 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2674907

The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Cette invention se rapporte à la découverte d'une signature pronostique moléculaire unique de 14 gènes utilisée pour prédire un cancer du sein métastatique. L'invention concerne en particulier des procédés et des réactifs permettant de détecter et de suivre les taux d'expression de ces gènes, ainsi que des procédés permettant d'utiliser les données concernant ces taux d'expression pour prédire le risque d'un cancer du sein métastatique.

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