A molecule which binds cd80 and cd86

Details A molecule which binds cd80 and cd86 A molecule which binds cd80 and cd86

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) C12N 5/20 (2006.01)

Patent

CA 2516832

The present invention relates to the identification of molecules, which are specific to CD80 and CD86 antigens. Also preferably, such antibodies are capable of inhibiting the binding of CD28 and CTLA-4 to those receptors. Those molecules are able to inhibit T cell mediated immune reactions.

La présente invention concerne l'identification de molécules qui sont spécifiques des antigènes CD80 et CD86. De préférence, de tels anticorps sont capables d'inhiber la liaison de CD28 et CTLA-4 à ces récepteurs. Lesdites molécules peuvent inhiber des réactions immunes à médiation de lymphocytes T.

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