C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) C07K 14/81 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2340460
The invention relates to a novel mutant of tissue factor pathway inhibitor (TFPI) protein and its corresponding DNA sequence. The mutant can be found in humans who show or may show an increased risk of thrombotic diseases. By screening samples of human blood for said DNA or fragments of it, it is possible to predict a disposition of thrombotic disorders by which prophylactic application or measures can be initiated.
L'invention concerne un nouveau mutant de la protéine de l'inhibiteur de la voie de la thromboplastine tissulaire, ainsi que la séquence d'ADN de celui-ci. On peut trouver ce mutant chez l'homme présentant ou susceptible de présenter un risque accru de maladies thrombotiques. En criblant des échantillon de sang humain pour rechercher ledit ADN ou des fragments de celui-ci, on peut établir une certaine prédisposition aux troubles thrombotiques, et on peut ainsi commencer à appliquer une prophylaxie ou des mesures prophylactiques.
Brinkmann Thomas
Goetting Christian
Kleesiek Knut
Prohaska Wolfgang
Schmidt Michael
Fetherstonhaugh & Co.
Kleesiek Knut
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