A mycoplasma gallisepticum antigen, dna encoding the...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 39/295 (2006.01) C07K 14/30 (2006.01) C07K 19/00 (2006.01) C12N 7/01 (2006.01) C12N 15/62 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2158024

A polypeptide showing an antigenicity to Mycoplasma gallisepticum, a fused polypeptide of said polypeptide ligated at the N terminus thereof with a signal membrane anchor of type II external membrane polypeptide of virus that infects to fowl, or a polypeptide showing an antigenicity which is substantially pure and reactive with Mycoplasma- immunized sera or Mycoplasma-infected sera, and having an amino acid sequence of about 32 kilodaltons, about 40 kilodaltons or about 70 kilodaltons, expression thereof or a modified polypeptide to such an extent that shows an immunogenicity equivalent to that of said polypeptide using a recombinant virus, and use of the recombinant virus as a live vaccine.

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