A nasal pharmaceutical composition

A - Human Necessities – 61 – K

Patent

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167/231

A61K 31/44 (2006.01) A61K 9/00 (2006.01) A61K 31/48 (2006.01)

Patent

CA 1103585

A NASAL PHARMACEUTICAL COMPOSITION Abstract of the Disclosure: The present invention provides a nasal pharmaceutical composition comprising as active agent a compound of formula I, Image I wherein R1 is hydrogen or halogen, R2 is hydrogen or alkyl of 1 to 4 carbon atoms, either (i) R 3 is isopropyl, sec-butyl, or isobutyl, R4 methyl, ethyl or isopropyl and R5 is hydrogen and R6 is hydrogen or methoxy or R5 and R6 are together a single bond, or (ii) R3 is benzyl, R4 is methyl, R5 is hydrogen and R6 is hydrogen or methoxy, in association with a pharmaceutically acceptable carrier or diluent, adapted for nasal administration.

290987

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