A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 31/445 (2006.01)
Patent
CA 2342341
The invention relates to a composition comprising a first component (a) which is (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5- carboxamide hydrogen (2R,3R)-tartrate monohydrate and a second component (b) which is paroxetine in the form of its free base, or a pharmaceutically acceptable salt and/or solvate thereof, the preparation thereof, pharmaceutical formulations containing said composition, use of and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition as well as a kit containing said composition.
L'invention concerne une composition constituée d'un premier constituant (a), un monohydrate de R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyrane-5-carboxamide hydrogène (2R, 3R)-tartrate, et d'un deuxième constituant (b), de la paroxétine sous forme de base libre, ou un sel et/ou un solvate pharmaceutiquement acceptable(s) de celle-ci; la préparation de cette composition; des formulations pharmaceutiques contenant ladite composition; une méthode de traitement de troubles affectifs tels que des troubles de l'humeur et des troubles anxieux à l'aide de ladite composition, et l'utilisation de ladite méthode de traitement; et une trousse contenant ladite composition.
Evenden John
Thorberg Seth-Olov
Astrazeneca Ab
Fetherstonhaugh & Co.
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