A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01)
Patent
CA 2342233
This invention relates to a composition comprising (R)-5-carbamoyl-8- fluoro-3- N,N- dicyclobutylamino-3, 4-dihydro-2H- 1-benzopyran in the form of the free base, or a pharmaceutically acceptable salt and/or solvate thereof, and (+)-1- [3-(dimethylamino)propyl]- 1-(p-fluorophenyl)- 5-phthlalancarbonitrile in the form of the free base, or a pharmaceutically acceptable salt and/or solvate thereof, the preparation thereof, pharmaceutical formulations containing said composition, use of and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition as well as a kit containing said composition.
L'invention concerne une composition constituée de (R)-5-carbamoyl-8- fluoro-3-N,N- dicyclobutylamino-3, 4-dihydro-2H-1- benzopyrane sous forme de base libre, ou d'un sel et/ou d'un solvate pharmaceutiquement acceptable(s) de celui-ci, et de (+)-1-[3-(diméthylamino)propyl]- 1-(p-fluorophényl)- 5-phtalancarbonitrile sous forme de base libre, ou d'un sel et/ou d'un solvate pharmaceutiquement acceptable(s) de celui-ci; la préparation de celle-ci; des formulations pharmaceutiques contenant ladite composition; une méthode de traitement de troubles affectifs tels que des troubles de l'humeur et des troubles anxieux à l'aide de ladite composition, et l'utilisation de ladite méthode de traitement; et une trousse contenant ladite composition.
Evenden John
Thorberg Seth-Olov
Astrazeneca Ab
Fetherstonhaugh & Co.
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