A new dosing regimen for ion channel modulating compounds...

A - Human Necessities – 61 – K

Patent

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A61K 31/40 (2006.01) A61P 9/06 (2006.01)

Patent

CA 2586918

Dosing regimens, routes of administration and methods for the treatment or prevention of arrhythmias are disclosed. In these methods, arrythmias (e.g. atrial fibrillation, atrial flutter, early afterdepolarizations and prolongation of QT interval) may be reduced or eliminated by administering ion channel modulating compounds to a subject in need thereof via the dosing regimens disclosed herein.

L'invention concerne des schémas posologiques, des voies d'administration et des méthodes de traitement d'arythmies. Ces méthodes (par exemple la fibrillation auriculaire, le flutter auriculaire, les post-dépolarisations précoces et la prolongation de l'intervalle Q-T) permettent de réduire ou d'éliminer les arythmies par administration de composés de modulation de canaux ioniques à un sujet nécessitant un tel traitement au moyen des schémas posologiques décrits dans l'invention.

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